I-OM Academy Certificate in Bioidentical Hormone Replacement Therapy (BHRT)
A Practical Systems-Medicine Approach to Hormone Evaluation, Prescribing, Monitoring, and Safety
Welcome to the I-OM Academy BHRT Certificate Course.
This 15-module professional certificate course is designed for a mixed health-professional audience, with prescribing clinicians as the primary audience.
The course emphasizes practical clinical reasoning, patient selection, hormone physiology, prescribing logic, monitoring, safety, risk management, and long-term treatment integration.
Practical prescribing and management content applies only within each learner’s lawful professional scope.
The course is U.S.-anchored in its regulatory, labeling, and product examples. International learners should verify local laws, product availability, labeling, professional guidance, and scope-of-practice requirements in their own jurisdiction.
Scope note: Gender-affirming hormone therapy is a distinct clinical field and is outside the primary scope of this certificate course. This scope boundary concerns the specialized hormone-treatment curriculum; it does not place transgender or gender-diverse patients outside the scope of respectful, evidence-based general clinical care.
This is an I-OM Academy professional certificate course. It is not currently accredited for CME/CE credit.
Completion of this course does not confer board certification, specialist status, licensure, expanded scope of practice, or independent prescriptive authority.
What You Will Learn
The course is designed to help learners understand not only which hormones may be considered, but also:
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when hormone therapy may or may not be appropriate
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how symptoms, physiology, laboratory findings, and metabolic context fit together
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how estrogen, progesterone, testosterone, DHEA, thyroid physiology, and related systems interact
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how route of administration affects pharmacology and clinical decision-making
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how to evaluate contraindications and risk
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how to monitor treatment over time
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how to recognize adverse effects and know when to modify, pause, or stop therapy
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how to integrate hormone therapy within the broader I-OM systems-medicine framework
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how to communicate uncertainty, evidence limitations, and informed consent clearly
Course Structure
The course consists of 15 modules, followed by a final examination.
Module 1 — Course Orientation, Scope, and Precise BHRT Terminology
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What “bioidentical hormone replacement therapy” means
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Evidence-based terminology
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Hormone optimization versus treatment of defined clinical indications
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Professional scope and legal boundaries
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Goals, limitations, and safety principles
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How to use this course
Module 2 — Hormone Physiology Across the Lifespan
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Estrogen, progesterone, testosterone, adrenal androgens, and thyroid physiology
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Hormone receptors and tissue effects
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Reproductive aging
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Perimenopause and menopause
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Male aging and androgen physiology
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Hormone interactions across organ systems
Module 3 — I-OM Systems Medicine Assessment of Hormone-Related Symptoms
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Symptoms versus underlying physiology
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Metabolic health and insulin resistance
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Stress physiology and cortisol
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The ICV framework: insulin, cortisol, and vitamin C
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Nutrient status and hormone metabolism
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Thyroid context
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Sleep, exercise, body composition, and lifestyle
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Why hormone therapy should not be evaluated in isolation
Module 4 — Indications, Non-Indications, and the Decision Not to Treat
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Appropriate clinical indications
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When symptoms may not be hormone-driven
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Avoiding treatment based on symptoms alone
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When lifestyle, metabolic, nutritional, or other interventions should come first
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When hormone therapy should be deferred or avoided
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Shared decision-making
Module 5 — Baseline Evaluation, Hormone Testing, Contraindications, and Risk Stratification
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Clinical history and examination
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Baseline laboratory evaluation
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Serum hormone testing
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Appropriate use and limitations of other testing modalities
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Timing and interpretation of testing
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Symptoms versus laboratory values
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Cardiovascular, thrombotic, cancer, hepatic, metabolic, and reproductive risk
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Contraindications and precautions
Module 6 — Estrogen Therapy: Indications, Routes, Formulations, and Dosing Logic
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Estradiol and other estrogens
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Oral versus transdermal therapy
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Vaginal estrogen
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Tissue-specific effects
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Benefits, limitations, and risks
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Starting-dose logic
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Dose adjustment
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Monitoring
Module 7 — Progestogens and Endometrial Safety
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Progesterone physiology
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Endometrial protection
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Micronized progesterone
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Progestins
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Routes and dosing principles
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Sleep and neurological effects
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Abnormal bleeding
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Monitoring and safety
Module 8 — Menopausal Hormone Therapy in Practice
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Perimenopause
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Early menopause
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Later menopause
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Vasomotor symptoms
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Genitourinary symptoms
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Bone health
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Individualized treatment priorities
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Adjusting therapy over time
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Combined estrogen-progestogen strategies
Module 9 — Testosterone Deficiency in Men: Diagnosis and Treatment Selection
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Male androgen physiology
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Diagnostic principles
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Symptoms versus biochemical findings
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Treatment indications
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Injectable, transdermal, and other delivery approaches
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Fertility considerations
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Treatment goals
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Avoiding inappropriate therapy
Module 10 — Testosterone Monitoring: Prostate, Hematologic, Fertility, and Cardiovascular Safety
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Testosterone response monitoring
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Hematocrit and erythrocytosis
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Prostate considerations
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Fertility suppression
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Cardiovascular and blood-pressure considerations
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Dose adjustment
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Adverse effects
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Change and stop rules
Module 11 — Androgens and Other Hormones in Women: Evidence and Boundaries
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Testosterone physiology in women
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Evidence-based indications
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Sexual function
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Muscle, bone, mood, and energy
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Avoiding excessive androgen exposure
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DHEA and adrenal androgens
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Potential benefits and adverse effects
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Appropriate monitoring
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Areas where evidence remains limited
Module 12 — Cancer-Related Considerations and Organ-Specific Surveillance
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Breast considerations
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Endometrial considerations
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Prostate considerations
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Cancer history and hormone therapy
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Screening and surveillance
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Risk communication
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Areas of uncertainty
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When specialist involvement is appropriate
Module 13 — Cardiovascular, Thrombotic, Metabolic, Neurologic, and Body-Composition Considerations
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Cardiovascular disease
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Venous thromboembolism
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Stroke risk
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Migraine
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Liver disease
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Insulin sensitivity
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Adiposity and body composition
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Muscle and bone
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Nutrition
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Resistance training
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Integrating metabolic health with hormone management
Module 14 — FDA-Approved vs Compounded Products, Practical Pharmacology, Evidence Controversies, and Informed Consent
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FDA-approved hormone products
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Compounded preparations
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Oral, transdermal, vaginal, injectable, and pellet routes
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Advantages and limitations of different delivery methods
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Product quality and consistency
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Evidence controversies
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Labeling and regulatory considerations
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Communicating uncertainty
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Informed consent
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Avoiding unsupported claims
Module 15 — Monitoring, Adverse Effects, Change/Stop Rules, and Integrated Case Synthesis
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Clinical response
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Laboratory follow-up
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Imaging and screening
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Dose adjustment
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Adverse effects
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Deprescribing and discontinuation
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Long-term management
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Integrated clinical decision-making
Case-based synthesis includes:
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perimenopause
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surgical menopause
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metabolic dysfunction
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low libido
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osteopenia
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thyroid dysfunction
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testosterone deficiency in men
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complex multimorbidity
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treatment intolerance
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situations in which hormone therapy should not be initiated
Enrollment Options
Course Only — US$895
For learners who want the complete BHRT Certificate Course in a self-paced format.
Includes:
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full access to all 15 course modules
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practical clinical teaching and case-based learning
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course learning materials and study guidance
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final examination
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certificate eligibility after successfully meeting course and examination requirements
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3 months of I-OM.ai Plus Membership
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300 AI Credits per month during the included membership period
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ongoing access to the private BHRT course area
One-time course fee: US$895
Guided Program — US$1,595
For learners who want the complete course plus additional live educational support.
Includes everything in Course Only, plus:
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three 1-hour live group Q&A sessions
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one session per month over approximately 3 months
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opportunities to discuss course concepts, clinical reasoning, monitoring, safety, implementation, and selected case questions within the educational scope of the program
One-time program fee: US$1,595
The Guided Program does not include individual medical consultation, individual patient management, supplements, or one-to-one clinical supervision.
What Happens After Enrollment?
After successful enrollment:
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Sign in to your Community.I-OM.ai account.
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Your account will receive access to the private BHRT Certificate Course area.
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Begin with Module 1 — Course Orientation, Scope, and Precise BHRT Terminology.
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Complete all 15 modules in order.
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Proceed to the BHRT Final Examination.
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After successfully meeting the examination and safety requirements, you will be eligible to receive your I-OM Academy BHRT Certificate.
Final Examination
After completing all 15 modules, learners proceed to the BHRT Final Examination.
The final assessment will evaluate:
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overall course knowledge
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clinical reasoning
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prescribing and treatment-selection principles
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monitoring
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contraindications
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adverse-effect recognition
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critical safety mastery
To successfully complete the certificate requirements, learners must:
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complete all 15 modules
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complete the final examination
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achieve an overall score of 80% or higher
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correctly answer all designated safety-critical questions
Certificate
Learners who successfully complete the course and meet the final examination requirements will be eligible for the:
I-OM Academy Certificate in Bioidentical Hormone Replacement Therapy (BHRT)
The certificate recognizes successful completion of the I-OM Academy educational program and assessment requirements.
It does not represent medical licensure, board certification, specialist certification, independent prescribing authority, or expanded professional scope.
Course Fee Policy
Enrollment is subject to the I-OM Academy Course Fee Policy.
Course fees are non-refundable once course access has been provided, except where required by applicable law.
I-OM Academy
Integrative Orthomolecular Systems Medicine
United States of America